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Physicians Urged to Review,
Consult Beers List
Mark H. Beers, M.D., might not be at
the top of your mind when you pull out your prescribing pad for
a patient over age 65 — but maybe he should be.
Beers was the senior researcher who pulled together a group of
12 geographically diverse medical experts in 1991 to compile a list
of drugs with potential adverse indications for senior patients.
The group has updated its criteria — known as the Beers List
— twice since then, most recently in 2003.
While the Beers List is not evidence-based, it does represent thoughtful
consensus about which medications may pose risks to older patients.
Under a physician’s clinical judgment, some of the listed
medications might be worthwhile, based on relative contraindications,
while others should be avoided.
Why use the list?
“In seniors, the drugs on the Beers List generally interfere
with motor skills and mental capabilities — which can enhance
the likelihood of a senior falling, stumbling, not walking properly
or having some activities of daily living become more difficult,”
cautioned Robert Pope, M.D., chief medical officer, Humana senior
products. “On the mental side, they may slow down recognition
or the ability to concentrate and focus. All of these effects increase
the risk of other, serious injuries for seniors.”
Yet many older Americans take these drugs. In 2006, a Humana study
of claims found that medications on the Beers List accounted for
$77 million in prescriptions for Humana members over 65 years old.
“For some medications on the list, such as skeletal muscle
relaxants, there’s a real safety issue,” Pope said.
“People released from the hospital may, as an effect of the
medication, lose their balance, fall and break a hip.”
Pope noted that the lifestyle and economic impacts resulting from
drugs prescribed without due consideration could be staggering when
falls and their after-effects are taken into account.
What is Humana doing?
Humana encourages physicians to refamiliarize themselves with the
Beers List and review it when prescribing for seniors. In addition,
Humana is taking the following steps:
- Humana’s pharmacy claims processor is now sending warning
messages to pharmacists regarding certain drugs on the list.
- Humana’s mental health provider, Corphealth, is sending
letters to physicians alerting them to potential drug issues.
- Humana’s member safety committee is looking into a “falls
prevention” program that would examine the location, cause
and effects of falls in seniors in an effort to reduce their occurrence.
“All doctors have been trained on the Beers List, and we
know the potential side effects of these medications,” Pope
said. “Probably, however, most of us haven’t reviewed
the list in quite some time. It’s a good time for doctors
to look at the list, be reminded what it contains and use sound
clinical judgment when prescribing to seniors.”
| Medications on the Revised
Beers List |
A
|
|
| alprazolam (Xanax) |
hydroxyzine (Vistaril, Atarax) |
| amiodarone (Cordarone) |
hyoscyamine (Levsin, Levsinex) |
| amitriptyline (Elavil) |
I |
| amphetamines |
indomethacin (Indocin, Indocin SR) |
| anorexic agents |
isoxsuprine (Vasodilan) |
| B |
K |
| barbiturates |
ketorolac (Toradol) |
| belladonna alkaloids (Donnatal) |
L |
| bisacodyl (Dulcolax) |
lorazepam (Ativan) |
| C |
M |
| carisoprodol (Soma) |
meperidine (Demerol) |
| cascara sagrada |
meprobamate (Miltown, Equanil) |
| chlordiazepoxide (Librium, Mitran) |
mesoridazine (Serintil) |
| chlordiazepoxide-amitriptyline
(Limbitrol) |
metaxalone (Skelaxin) |
| chlorpheniramine (Chlor-Trimeton) |
methocarbamol (Robaxin) |
| chlorpropamide (Diabinese) |
methyldopa (Aldomet) |
| chlorzoxazone (Paraflex) |
methyldopa-hydrochlorothiazide (Aldoril) |
| cimetidine (Tagamet) |
methyltestosterone (Android, Virilon, Testrad) |
| clidinium-chlordiazepoxide (Librax) |
mineral oil |
| clonidine (Catapres) |
N |
| clorazepate (Tranxene) |
naproxen (Naprosyn, Avaprox, Aleve) |
| cyclandelate (Cyclospasmol) |
Neoloid |
| cyclobenzaprine (Flexeril) |
nifedipine (Procardia, Adalat) |
| cyproheptadine (Periactin) |
nitrofurantoin (Microdantin) |
| D |
O |
| dessicated thyroid |
orphenadrine (Norflex) |
| dexchlorpheniramine (Polaramine) |
oxaprozin (Daypro) |
| diazepam (Valium) |
oxazepam (Serax) |
| dicyclomine (Bentyl) |
oxybutynin (Ditropan) |
| digoxin (Lanoxin) |
P |
| diphenhydramine (Benadryl) |
pentazocine (Talwin) |
| dipyridamole (Persantine) |
perphenazine-amitriptyline (Triavil) |
| disopyramide (Norpace, Norpace CR) |
piroxicam (Feldene) |
| doxazosin (Cardura) |
promethazine (Phenergan) |
| doxepin (Sinequan) |
propantheline (Pro-Banthine) |
| E |
propoxyphene (Darvon) and combination products |
| ergot mesyloids (Hydergine) |
Q |
| estrogens |
quazepam (Doral) |
| ethacrynic acid (Edecrin) |
R |
| F |
reserpine (Serpalan, Serpasil) |
| ferrous sulfate (iron) |
T |
| fluoxetine (Prozac) |
temazepam (Restoril) |
| flurazepam (Dalmane) |
thioridazine (Mellaril) |
| G |
ticlopidine (Ticlid) |
guanadrel (Hylorel) |
triazolam (Halcion) |
| guanethidine (Ismelin) |
trimethobenzamide (Tigan) |
| H |
tripelennamine |
| halazepam (Paxipam) |
|
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