Generic Drug Guide

Generic drug guide

Generic alternatives and generic equivalents to brand-name medications may help patients save money. The U.S. Food and Drug Administration (FDA) states that it ensures the safety and effectiveness of the generic drugs it approves.1 According to the FDA, a generic drug is identical, or bioequivalent, to a brand-name drug and is “required to have the same active ingredient, strength, dosage form and route of administration as the brand-name product.”2 A generic alternative is not a direct generic for a particular branded medication, but in most cases it is in the same therapeutic class as the brand. Alternative drugs produce similar clinical outcomes and often have similar side-effect profiles.

Generic drug options

Please refer to the chart below for a list of common brand drugs and corresponding generic and over-the-counter (OTC) alternatives. When a generic equivalent to a brand is listed below, this format is used: name of equivalent generic followed by brand name in parentheses [e.g., benazepril (Lotensin)]. You can also download a printable version of the chart.

Therapeutic class Brand products Generic and over-the-counter (OTC) alternatives
Angiotensin-converting enzyme(ACE) inhibitors Accupril, Aceon, Altace, Capoten, Lotensin, Mavik, Monopril, Prinivil, Univasc, Vasotec, Zestril benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), trandolapril (Mavik)
Angiotensin II receptor blockers (ARBs) Atacand, Avapro, Benicar, Cozaar, Diovan, Edarbi, Hyzaar, Micardis, Teveten candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), telmisartan (Micardis), valsartan (Diovan)
Angiotensin II receptor antagonist/combinations Atacand HCT, Avalide, Benicar HCT, Diovan HCT, Exforge, Exforge HCT, Micardis HCT, Teveten HCT candesartan/HCTZ (Atacand HCT), eprosartan/HCTZ (Teveten HCT), irbesartan/HCTZ (Avalide), losartan/ HCTZ (Hyzaar), telmisartan/HCTZ (Micardis HCT), valsartan/amlodipine (Exforge), valsartan/amlodipine/HCTZ (Exforge HCT), valsartan/HCTZ (Diovan HCT)
Antibiotics Augmentin, Augmentin ES, Augmentin XR, Avelox, Cipro, Levaquin, Zithromax amoxicillin/clavulanate (Augmentin, Augmentin ES, Augmentin XR), azithromycin (Zithromax), ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Avelox)
Anticoagulants Arixtra, Coumadin, Eliquis, Jantoven, Lovenox, Pradaxa, Savaysa, Xarelto enoxaparin injection (Lovenox), fondaparinux injection (Arixtra), warfarin (Coumadin, Jantoven)
Antidepressants Celexa, Cymbalta, Effexor XR, Fetzima, Irenka, Khedezla, Lexapro, Marplan, Paxil, Paxil CR, Pristiq, Prozac, Sarafem, Savella, Wellbutrin, Wellbutrin XL, Viibryd bupropion (Wellbutrin), bupropion XL (Wellbutrin XL), citalopram (Celexa), desvenlafaxine (Pristiq), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), fluvoxamine CR (Luvox CR), nefazodone (Serzone), paroxetine (Paxil), paroxetine CR (Paxil CR), sertraline (Zoloft), venlafaxine (Effexor), venlafaxine XR (Effexor XR)
Antiemetic agents Anzemet, Compro, Emend, Kytril, Reglan, Tigan, Zofran, Zofran ODT, Zuplenz granisetron (Kytril), metoclopramide (Reglan), ondansetron (Zofran, Zofran ODT, Zuplenz), prochlorperazine (Compro), trimethobenzamide (Tigan)
Antiepileptic drugs Aptiom, Banzel, Carbatrol, Depakote, Depakote ER, Diamox, Epitol, Felbatol, Fycompa, Gabitril, Keppra, Keppra XR, Lamictal, Lamictal XR, Lyrica, Neurontin, Oxtellar XR, Potiga, Sabril, Qudexy XR, Tegretol, Topamax, Trileptal, Trokendi XR, Vimpat, Zonegran acetazolamide (Diamox), carbamazepine (Carbatrol, Epitol, Tegretol, Tegretol XR), divalproex (Depakote), divalproex extended release (Depakote ER), felbamate (Felbatol), gabapentin (Neurontin), lamotrigine (Lamictal), lamotrigine ER (Lamictal XR), levetiracetam (Keppra), levetiracetam extended-release (Keppra XR), oxcarbazepine (Trileptal), tiagabine (Gabitril), topiramate (Topamax), valproic acid (Depakote), zonisamide (Zonegran)
Antifungals Ancobon, Diflucan, Grifulvin V, Gris- Peg, Lamisil, Nizoral, Terbinex, VFend fluconazole (Diflucan), flucytosine (Ancobon), griseofulvin (Grifulvin V, Gris-Peg), ketoconazole (Nizoral), nystatin (Mycostatin, Nystop), terbinafine (Lamisil), voriconazole (VFend)
Antiglaucoma agents Azopt, Betagan, Betimol, Cosopt, Istalol, Lumigan, Ocupress, Rescula, Timoptic, Travatan, Travatan Z, Trusopt, Xalatan, Zioptan Betaxolol (Betoptic), bimatoprost (Lumigan), carteolol (Ocupress), dorzolamide (Trusopt), dorzolamide/timolol (Cosospt), latanoprost (Xalatan), levobunolol (Betagan), metipranolol (OptiPranolol), timolol (Betimol, Istalol, Timoptic), travoprost (Travatan)
Antihistamines Allegra OTC, Allegra-D OTC, Clarinex, Clarinex-D, Claritin OTC, Claritin-D OTC, Xyzal, Zyrtec OTC, Zyrtec-D OTC desloratadine (Clarinex), fexofenadine OTC (Allegra OTC), fexofenadine/ pseudoephedrine (Allegra-D OTC), levocetirizine (Xyzal), loratadine OTC (Claritin OTC), loratadine/pseudoephedrine OTC (Claritin-D OTC), cetirizine OTC (Zyrtec OTC), cetirizine/ pseudoephedrine OTC (Zyrtec-D OTC)
Antimigraine agents Alsuma, Amerge, Axert, Frova, Imitrex, Maxalt, Relpax, Sumavel, Treximet, Zomig almotriptan (Axert), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), zolmitriptan (Zomig)
Antiplatelet Aggrenox, Brilinta, Effient, Plavix clopidogrel (Plavix), dipyridamole/aspirin (Aggrenox), ticlopidine (Ticlid)
Antiparkinsonian agents Apokyn, Azilect, Comtan, Eldepryl, Neupro, Mirapex, Parlodel, Requip, Requip XL, Stalevo, Tasmar benztropine* (Cogentin), bromocriptine (Parlodel, Cycloset), cabergoline (Dostinex), entacapone (Comtan), pramipexole (Mirapex), ropinirole (Requip), ropinirole extended release (Requip XL), tolcapone (Tasmar), trihexyphenidyl* (Artane)
Antiretrovirals Combivir, Emtriva, Epivir, Epzicom, Retrovir, Trizivir, Videx, Viramune, Zerit, Ziagen abacavir (Ziagen), abacavir/lamivudine/zidovudine (Trizivir), didanosine (Videx), lamivudine (Epivir), lamivudine/zidovudine (Combivir), nevirapine (Viramune), stavudine (Zerit), zidovudine (Retrovir)
Antispasmodics Detrol, Detrol LA, Ditropan, Ditropan XL, Enablex, Gelnique, Myrbetriq, Oxytrol, Pamine, Sanctura, Sanctura XR, Toviaz, Vesicare flavoxate (Urispas), oxybutynin (Ditropan), oxybutynin ER* (Ditropan XL), tolterodine (Detrol), tolterodine ER (Detrol LA), trospium (Sanctura)
Antivirals Copegus, Cytovene, Famvir, Flumadine, Sitavig, Valcyte, Valtrex, Zovirax acyclovir (Zovirax), famciclovir (Famvir), ganciclovir (Cytovene), ribavirin (Copegus), rimantadine (Flumadine), valacyclovir (Valtrex), valganciclovir (Valcyte)
Benign prostatic hyperplasia (BPH) agents Avodart, Cardura*, Cardura XL*, Flomax, Hytrin*, Jalyn, Proscar, Rapaflo, Uroxatral alfuzosin SR (Uroxatral), doxazosin* (Cardura), finasteride (Proscar), tamsulosin (Flomax), terazosin* (Hytrin)
Beta blockers Bystolic, Coreg, Coreg CR, Inderal LA, Lopressor, Tenoretic, Tenormin, ToprolXL, Zebeta, Ziac atenolol (Tenormin), atenolol/chlorthalidone (Tenoretic), bisoprolol (Zebeta), bisoprolol/HCTZ (Ziac), carvedilol (Coreg, Coreg CR), metoprolol (Lopressor), metoprolol XL (Toprol-XL), propranolol LA (Inderal LA)
Bisphosphonates Actonel, Atelvia, Boniva, Fosamax alendronate (Fosamax), ibandronate (Boniva), risedronate (Actonel)
Calcium channel blockers Adalat CC, Caduet, Calan, Cardene, DynaCirc CR, Lotrel, Norvasc, Sular, Plendil amlodipine (Norvasc), amlodipine/benazepril (Lotrel), amlodipine/atorvastatin (Caduet), diltiazem (Cardizem, Cartia XT, Dilt-CD, Tiazac), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat CC), nisoldipine (Sular), verapamil (Calan)
Cholinesterase/N-methyl-D-aspartate (NMDA) inhibitors Aricept, Exelon, Namenda, Razadyne, Razadyne ER donepezil (Aricept), galantamine (Razadyne), galantamine ER (Razadyne ER), rivastigmine (Exelon)
Nasal corticosteroids Beconase AQ, Flonase, Nasarel, Nasonex, Nasacort AQ, QNASL, Rhinocort Aqua, Veramyst, Zetonna budesonide (Rhinocort Aqua), fluticasone (Flonase OTC), flunisolide (Nasarel), triamcinolone (Nasacort OTC)
Opioids Abstral, Actiq, Avinza, Butrans, Demerol, Dilaudid, Dolophine, Duragesic, Embeda, Exalgo, Fentora, Hysingla ER, Ibudone, Kadian, MS Contin, Opana ER, Oramorph SR, Oxycontin, Reprexain, Subutex, Suboxone, Zohydro ER buprenorphine (Buprenex, Subutex, Suboxone), butorphanol (Stadol), codeine sulfate, fentanyl transdermal patch (Duragesic), hydromorphone (Dilaudid), levorphanol (Levo-Dromoran), meperidine (Demerol), methadone (Dolophine), morphine sulfate (Avinza), morphine sulfate ER (MS Contin/Oramorph SR), oxycodone (Oxycontin), oxymorphone ER (Opana ER), tramadol (Ultram)
Ophthalmic agents: antihistamine Bepreve, Elestat, Emadine, Lastacaft, Naphcon, Optivar, Pataday, Patanol, Pazeo azelastine (Optivar), epinastine (Elestat), ketotifen (Zaditor OTC), naphazoline (Naphcon)
Ophthalmic agents: NSAID Acular, Acular LS, Acular PF, Acuvail, Bromday, Ilevro, Nevanac, Ocufen, Prolensa, Voltaren, Xibrom bromfenac (Xibrom), diclofenac (Voltaren), flurbiprofen (Ocufen), ketorolac (Acular/LS/PF)
Proton pump inhibitors Aciphex, Dexilant, Nexium, Prevacid, Prevacid SoluTab, Prilosec, Protonix, Zegerid esomeprazole (Nexium OTC), lansoprazole (Prevacid OTC), omeprazole (Prilosec OTC), omeprazole/ sodium bicarbonate (Zegerid OTC), pantoprazole (Protonix), rabeprazole (Aciphex)
Sedative-hypnotics† Ambien, Ambien CR, Belsomra, Edluar, Intermezzo, Lunesta, Restoril, Rozerem, Silenor, Sonata eszopiclone (Lunesta), temazepam (Restoril), trazodone (Desyrel), zaleplon (Sonata), zolpidem (Ambien), zolpidem CR (Ambien CR)
Statins Crestor, Lescol, Lescol XL, Lipitor, Livalo, Mevacor, Pravachol, Vytorin, Zocor atorvastatin (Lipitor), fluvastatin (Lescol, Lescol XL), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor)
Stimulants Adderall, Adderall XR, Aptensio XR, Concerta, Daytrana, Focalin XR, Vyvanse, Zenzedi dextroamphetamine salts extended-release (Adderall and Adderall XR), methylphenidate (Concerta)

*May not be appropriate for persons ages 65 years and older; † indicated for short-term use only.

Please note: The information provided here does not include an exhaustive list of drug contraindications or recommended restrictions and precautions for all patients.

References:

1. U.S. Food and Drug Administration, "Your generic drug is safe and effective. And we've got the results to prove it,"

http://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/UnderstandingGenericDrugs/ucm173738.htm, accessed Jan. 20, 2016.

2. U.S. Food and Drug Administration, "Facts about Generic Drugs,"

http://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/UnderstandingGenericDrugs/ucm167991.htm, accessed Jan. 19, 2016.