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Is a statin right for you?

How can statin therapy reduce the risk of heart attack and stroke?

Statins are a group of medicines that work to lower your cholesterol. According to the American Heart Association, statins are able to lower cholesterol by blocking a substance your body needs to make cholesterol. Statins may also help your body reabsorb the cholesterol in your arteries, which could be causing blockages. Statins also help lower triglycerides (blood fats) and raise your good cholesterol (HDL) levels.1 By doing this, the lower cholesterol levels may prevent heart disease or strokes.2

Some common names of statins are atorvastatin, simvastatin, rosuvastatin, pravastatin, lovastatin.

Do you need a statin?

Know your risks

You don't want your first sign of heart disease to be a heart attack. That's why it's so important to know what your risk of heart disease may be—heart disease is the leading cause of death in this country for both men and women.3

Risk factors for heart attack and stroke:4

  • High cholesterol
  • High blood pressure
  • Smoking
  • Obesity
  • Physical inactivity
  • Poor diet

Answer the following questions to learn more about your risk for a heart attack.

Start assessment - English

It’s important to talk to your doctor about your heart health and other risk factors. We’ve put together this statin checklist, PDF to bring to your next doctor appointment.

Taking statins for heart disease and diabetes

Statins can be prescribed for people who have high cholesterol, but they can also help people who don't have high cholesterol. If you've had a heart attack or stroke, or have diabetes, you are at a higher risk for future heart attacks or strokes. Statins can help reduce the risk of having a heart attack or stroke even if you do not have high cholesterol.5

Possible side effects and interactions

Side effects

Muscle and liver problems are rare but possible side effects of a statin.6 There are tests your doctor can perform to monitor muscle and liver function. Side effects can be managed. Always talk to your dotor if you experience any side effects or unusual symptoms while taking a statin.

Your doctor may be able to switch you to another statin with a lower risk of side effects.

Interactions

Some statin medications can interact with food, drink and other medications. Make sure your doctor knows all of the prescription and non-prescription medications you take and talk with them about possible food-related interations. Below are some common drug and food interactions with statins.7

  • Amiodarone
  • Amlodipine and diltiazem
  • Antibiotics (such as erythromycin)
  • Antifungals (such as ketoconazole)
  • Digoxin
  • Gemfibrozil
  • Phenytoin
  • Warfarin
  • Grapefruit and grapefruit juice

Explore more medication articles

Sources:

  1. “Cholesterol medications,” American Heart Association, last accessed July 7, 2023, https://www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia/cholesterol-medications , opens new window.
  2. “Statins: Are these cholesterol-lowering drugs right for you?,” Mayo Clinic, last accessed July 7, 2023, https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statins/art-20045772 , opens new window.
  3. “Leading causes of death,” Centers for Disease Control and Prevention, last accessed July 7, 2023, https://www.cdc.gov/nchs/fastats/leading-causes-of-death.htm , opens new window.
  4. “Heart disease and stroke,” Centers for Disease Control and Prevention, July 7, 2023, https://www.cdc.gov/chronicdisease/resources/publications/factsheets/heart-disease-stroke.htm , opens new window.
  5. “Statins: Are these cholesterol-lowering drugs right for you?”
  6. “Statins: Are these cholesterol-lowering drugs right for you?”
  7. M P Vaquero , et. al, “Major diet-drug interactions affecting the kinetic characteristics and hypolipidaemic properties of statins,” PubMed.gov, last accessed July 7, 2023, https://pubmed.ncbi.nlm.nih.gov/20449528/ , opens new window.